Author Archive for: admin Z.9

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Entries by admin Z.9

Editorial: The trials of doing trials: will the prostatic stent rise from the dead?

A further re‐engineering of the prostatic stent (temporary implantable nitinol device [TIND®, Medi‐Tate Ltd., Israel]) is reported by Porpiglia et al. 1 in this edition of the BJUI. Enthusiasm for novel ‘minimally invasive’ treatments for BPH/LUTs has surged recently, with new options supported by strong data becoming available 2, 3. That interest reflects the continuing desire of our patients to seek […]

Article of the Month: MRI supported transperineal prostate biopsy

Every Month, the Editor-in-Chief selects an Article of the Month from the current issue of BJUI. The abstract is reproduced below and you can click on the button to read the full article, which is freely available to all readers for at least 30 days from the time of this post. In addition to the […]

July 2018 – About the Cover

This issue’s Article of the Month is a multicentre trial led by researchers in Cambridge, UK. The cover shows a typical Cambridge scene of bicycles leaning against a college wall. Cambridge is home to the world-renowned University of Cambridge, which was founded in 1209. The city’s skyline is dominated by several college buildings, along with the spire […]

Editorial: β3‐adrenoceptor agonists inhibit calcium oscillations in bladder detrusor

The β3‐adrenoceptor (β3‐AR) agonist mirabegron has now been used clinically for the treatment for overactive bladder (OAB) for 5 years, but it is still not clear either exactly where the β3‐ARs are located within the bladder wall or entirely how they work. β3‐AR agonists can reduce detrusor contractions after cholinergic stimulation, but the concentrations of mirabegron […]

Video: β3‐adrenoceptor agonists inhibit carbachol‐evoked Ca2+ oscillations in murine detrusor myocytes

 β3‐adrenoceptor agonists inhibit carbachol‐evoked Ca2+ oscillations in murine detrusor myocytes   Abstract Objective To test if carbachol (CCh)‐evoked Ca2+ oscillations in freshly isolated murine detrusor myocytes are affected by β3‐adrenoceptor (β‐AR) modulators. Materials and Methods Isometric tension recordings were made from strips of murine detrusor, and intracellular Ca2+ measurements were made from isolated detrusor myocytes using […]

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