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Eoin Dinneen, Aiman Haider, Jack Grierson, Alex Freeman, Jon Oxley, Tim Briggs, Senthil Nathan, Norman R Williams, Chris Brew‐Graves, Raj Persad, Jon Aning, Charles Jamieson, Marzena Ratynska, Imen Ben‐Salha, Rhys Ball, Rosie Clow, Clare Allen, Daniel Heffernan‐Ho, John Kelly, Greg Shaw

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Entries by Eoin Dinneen, Aiman Haider, Jack Grierson, Alex Freeman, Jon Oxley, Tim Briggs, Senthil Nathan, Norman R Williams, Chris Brew‐Graves, Raj Persad, Jon Aning, Charles Jamieson, Marzena Ratynska, Imen Ben‐Salha, Rhys Ball, Rosie Clow, Clare Allen, Daniel Heffernan‐Ho, John Kelly, Greg Shaw

NeuroSAFE frozen section during robot‐assisted radical prostatectomy (RARP): Peri‐operative and Histopathological Outcomes from the NeuroSAFE PROOF Feasibility Randomised Controlled Trial

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Abstract Objectives To report on the methods, peri‐operative outcomes and histopathological concordance between frozen and final section from the NeuroSAFE PROOF Feasibility study (NCT03317990). Patients and Methods Between May 2018 and March 2019 49 men at 2 UK centres underwent robot‐assisted robotic prostatectomy (RARP). 25 men were randomised to NeuroSAFE RARP (intervention arm) vs. 24 […]

Complications of synthetic mesh inserted for stress urinary incontinence

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Abstract Objective To assess the differential response to neoadjuvant chemotherapy (NAC) in patients with UCB compared to UTUC treated with radical surgery. Materials and methods Data from 1299 patients with UCB and 276 with UTUC were obtained from multicentric collaborations. The association of disease location (UCB vs UTUC) with pathologic complete response (pCR; defined as […]

Perioperative Outcomes and Cost of Robotic Versus Open Simple Prostatectomy in the Modern Robotic Era: Results from the National Inpatient Sample

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Abstract Objective To assess the differential response to neoadjuvant chemotherapy (NAC) in patients with UCB compared to UTUC treated with radical surgery. Materials and methods Data from 1299 patients with UCB and 276 with UTUC were obtained from multicentric collaborations. The association of disease location (UCB vs UTUC) with pathologic complete response (pCR; defined as […]

68Ga‐prostate‐specific membrane antigen tracers can alter the management of more than half of prostate cancer patients with biochemical recurrence

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Abstract Purpose To investigate the impact of 68Gallium prostate‐specific membrane antigen (68Ga‐PSMA) tracers on the management of prostate cancer patients with biochemical recurrence (BCR) by systematical review and meta‐analysis. Materials and Methods We performed a literature search on PubMed, Embase, and Web of Science databases up to October 29, 2019. We included studies that reported […]

Global Assessment of Urological Endoscopic Skills (GAUES): development and validation of a novel assessment tool to evaluate endourological skills

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Objectives To assess whether free PSA ratio (FPSAR) at biochemical recurrence (BCR) can predict metastasis, castrate‐resistant prostate cancer (CRPC), and cancer‐specific survival (CSS), following therapy for localised disease. Patients and Methods A single‐centre retrospective cohort study (NCT03927287) including a discovery cohort composed of patients with an FPSAR after radical prostatectomy (RP) or radiotherapy (RT) between […]

Genetic variability in 13q33 and 9q34 is linked to Aggressiveness Patterns and a Higher risk of progression of Non‐Muscle‐Invasive Bladder Cancer at the time of Diagnosis

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Objectives To assess whether free PSA ratio (FPSAR) at biochemical recurrence (BCR) can predict metastasis, castrate‐resistant prostate cancer (CRPC), and cancer‐specific survival (CSS), following therapy for localised disease. Patients and Methods A single‐centre retrospective cohort study (NCT03927287) including a discovery cohort composed of patients with an FPSAR after radical prostatectomy (RP) or radiotherapy (RT) between […]

Adjuvant radiotherapy in node positive prostate cancer patients: A debate still on. when, for whom?

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Objectives To present historical and contemporary hypotheses on the pathogenesis of benign prostatic hyperplasia (BPH), and the potential implications for current medical therapies. Methods The literature on BPH was reviewed. BPH is a prevalent disease with significant health and economic impacts on patients and health organisations across the world, whilst the cause/initiation of the disease […]

Cabozantinib plus Docetaxel and Prednisone in Metastatic Castrate Resistant Prostate Cancer

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Objectives To present historical and contemporary hypotheses on the pathogenesis of benign prostatic hyperplasia (BPH), and the potential implications for current medical therapies. Methods The literature on BPH was reviewed. BPH is a prevalent disease with significant health and economic impacts on patients and health organisations across the world, whilst the cause/initiation of the disease […]

Utility of Blood Tests in Screening for Metabolic Disorders in Kidney Stone Disease

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Abstract Objectives To determine the clinical utility of blood tests as a screening tool for metabolic abnormalities in patients with kidney stone disease. Subjects and Methods: Clinical and biochemical data from 709 patients attending the Oxford University Hospitals NHS Foundation Trust for assessment and treatment of kidney stones was prospectively collected between April 2011 and […]

Effect of losartan on the recoverability of renal function in anuric and oliguric patients with a solitary obstructed kidney: a double‐blind randomized placebo‐controlled trial

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Objectives To assess the role of the angiotensin receptor blocker losartan on the recoverability of renal function after de‐obstruction in patients with anuria and oliguria. Materials and Methods This was a double‐blind randomized placebo‐controlled trial in anuric or oliguric patients with calcular obstruction of solitary kidney. Patients with an anomalous kidney or those with an […]

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