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About Vincent Gnanapragasam, Tristan Barrett, Simon Pacey, Anne Warren

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Entries by Vincent Gnanapragasam, Tristan Barrett, Simon Pacey, Anne Warren

Does modern Active surveillance offer an opportunity for new therapeutic strategies in early prostate cancer?

Abstract National and international guidelines endorse AS as the preferred method of managing men with low‐risk disease and as an option for selected men with intermediate‐risk features (1). For this latter group there remains understandable anxiety on the part of many clinicians in pursuing a non‐interventional approach. This is both a limitation and also a […]

Reversing the effects of androgen deprivation therapy in men with metastatic castration resistant prostate cancer

Abstract Background Bipolar androgen therapy (BAT) is the cyclic administration of high dose testosterone as a novel treatment for metastatic castration resistant prostate cancer (mCRPC). We hypothesized that rapid testosterone cycling would promote improvements in body composition and these would be associated with improvements in lipid profiles, and quality‐of‐life. Methods Men from two completed trials […]

Open nephron sparing surgery in patients with a complex tumour in a solitary kidney: technical, oncological and functional outcomes

Abstract Nephron Sparing Surgery (NSS) is the established treatment of choice for most T1 renal masses (1). By contrast a large and/or endophytic mass usually requires radical nephrectomy (RN) to reduce the risk of disappointing oncological outcomes. Yet, when a complex mass arises in a solitary kidney and partial nephrectomy (PN) is imperative, the oncological […]

How reliable is surgeon reported data? : A comparison of the British Association of Urological Surgeons radical prostatectomy audit with the National Prostate Cancer Audit Hospital Episode Statistic linked database.

Abstract Nephron Sparing Surgery (NSS) is the established treatment of choice for most T1 renal masses (1). By contrast a large and/or endophytic mass usually requires radical nephrectomy (RN) to reduce the risk of disappointing oncological outcomes. Yet, when a complex mass arises in a solitary kidney and partial nephrectomy (PN) is imperative, the oncological […]

Robotic assisted pyeloplasty with a new robotic system KD‐SR‐01: a prospective, single‐center, single‐arm clinical study

Abstract Open Anderson‐Hynes dismembered pyeloplasty was the criterion standard for ureteropelvic junction obstruction. Laparoscopic pyeloplasty was comparable to open pyeloplasty in success rates while laparoscopic pyeloplasty offered the advantages of decreased morbidity, shorter hospital stay, and quicker recovery. While laparoscopic pyeloplasty was accompanied with the slow learning curve due to technically demanding and time‐consuming intracorporal […]

Loop‐tail stents fail in reducing stent‐related symptoms. Results of a prospective randomized controlled trial

Abstract Open Anderson‐Hynes dismembered pyeloplasty was the criterion standard for ureteropelvic junction obstruction. Laparoscopic pyeloplasty was comparable to open pyeloplasty in success rates while laparoscopic pyeloplasty offered the advantages of decreased morbidity, shorter hospital stay, and quicker recovery. While laparoscopic pyeloplasty was accompanied with the slow learning curve due to technically demanding and time‐consuming intracorporal […]

Retrosigmoid ileal conduit without transposition of the left ureter after open radical cystectomy for bladder cancer

Objectives To examine the gender‐related differences in the presentation, management and outcomes of patients admitted with acute renal colic at our institution. Patients and Methods A retrospective analysis of 231 consecutive patients requiring inpatient admission for acute renal colic between October 2015 and March 2018. For each admission, data on demographics, admission blood results, stone […]

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