Author Archive for: Christopher Chapple

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Entries by Christopher Chapple

Editorial: A contemporary view on the use of slings and artificial urinary sphincters for the treatment of post‐prostatectomy incontinence in England

Post‐prostatectomy urinary incontinence (UI) is a well‐recognised consequence of radical prostatectomy carried out as treatment for organ‐confined prostate cancer. This interesting article [1] reviews the in-practice surgical management of post‐prostatectomy UI in England over an 8‐year period, using the Hospital Episodes Statistics (HES) database. In total, 1414 patients had an artificial urinary sphincter (AUS) implanted, with a […]

Editorial: Mirabegron the first β3-adrenoceptor agonist for OAB: a summary of the phase III studies

The study reported in this edition of BJUI details the results of a large phase III study conducted in Japan contrasting 50 mg mirabegron, the new β3-adrenoceptor agonist, to placebo with tolterodine as an active comparator [1]. This adds to the body of knowledge already provided by phase III evaluations reported from Europe [2], where tolterodine […]

Editorial: Think irritable bowel syndrome when treating overactive bladder

The bladder and bowel are functionally related organs; they lie in close proximity, have similar innervations and some structural similarities, albeit having different functional characteristics; they are both critical for the storage, collection and expulsion of waste products. Several previous clinical reports have suggested that LUTS, such as overactive bladder syndrome (OAB), can occur concurrently with disorders of the colon, such […]

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