Author Archive for: Karl-Erik Andersson

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Entries by Karl-Erik Andersson

Editorial: Oxidative stress and lower urinary tract symptoms: cause or consequence?

April 24, 2019/by Karl-Erik Andersson

Oxidative stress has been defined as ‘an imbalance between oxidants and anti-oxidants in favour of the oxidants, leading to a disruption of redox signalling and control and/or molecular damage’ [1]. Reactive oxygen and nitrogen species (ROS/RNS) produced under oxidative stress are known to damage all cellular biomolecules (lipids, sugars, proteins and polynucleotides). ROS/RNS is often […]

Editorial: Mechanisms of ATP release – future therapeutic targets?

June 24, 2015/by Karl-Erik Andersson

When Ferguson et al. [1] demonstrated ATP release from the rabbit bladder and concluded: ‘… ATP is released from the urothelium as a sensory mediator … ’, they opened a new field of research with focus on urothelial signaling mechanisms and afferent nerve functions in bladder control. Other investigators have shown, in several animal models, that […]