Objective To assess the activity and safety of sequential lutetium-177 (177Lu)-PSMA-617 and docetaxel vs docetaxel on a background of androgen deprivation therapy (ADT) in men with de novo metastatic hormone-naïve prostate cancer (mHNPC). Patients and Methods UpFrontPSMA (NCT04343885) is an open-label, randomized, multicentre, phase 2 trial, recruiting 140 patients at 12 Australian centres. Key eligibility […]
Objective To assess the activity and safety of sequential lutetium-177 (177Lu)-PSMA-617 and docetaxel vs docetaxel on a background of androgen deprivation therapy (ADT) in men with de novo metastatic hormone-naïve prostate cancer (mHNPC). Patients and Methods UpFrontPSMA (NCT04343885) is an open-label, randomized, multicentre, phase 2 trial, recruiting 140 patients at 12 Australian centres. Key eligibility […]
Part of the BURST/BJUI podcast series BJUI – BJU International · BURST podcast: NICE Bedwetting In Under 19s Podcast: NICE guidance: bedwetting in under 19s Tara Burnhope is a Specialty Registrar in Urology in the West Midlands Deanery and an active member of BURST.
Part of the BURST/BJUI podcast series BJUI – BJU International · BJUI/BURST: The IDENTIFY Study Podcast: The IDENTIFY Study: The investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer; a multicentre observational study Mr Sinan Khadhouri is a Specialty Registrar in Urology in the East of Scotland and currently doing his […]
Objective To review the utility of vesicourethral anastomosis (VUA)‐directed biopsy in the setting of biochemical recurrence (BCR) after radical prostatectomy (RP) for prostate cancer (PCa) in patients who have undergone evaluation by gallium‐68 prostate‐specific membrane antigen positron emission tomography with computed tomography (68Ga‐PSMA PET/CT). Methods We completed a retrospective review of a prospectively maintained dataset […]
Objectives To establish the healthcare factors that contribute to testicular torsion adverse events (orchidectomies) and ‘near misses’. The secondary objective was to identify areas suitable for impactful quality improvement initiatives to be undertaken by National Health Service (NHS) healthcare providers nationally. Materials and Methods This was a retrospective record review and analysis, carried out in […]
Objectives To develop and validate a model to predict 12‐month continence status after robot‐assisted radical prostatectomy (RARP) from preoperative and 3‐month postoperative data; this model could help in informing patients on their individualised risk of urinary incontinence (UI) after RP in order to choose the best treatment option. Patients and Methods Data on 9421 patients […]
Aim To assess trends in the incidence, disease management and survival rates for upper urinary tract urothelial carcinoma (UTUC) in the Netherlands. Materials and methods Patients diagnosed with primary UTUC in the Netherlands between 1993 and 2017 were identified through the population‐based Netherlands Cancer Registry (NCR). Patient and tumour characteristics, as well as information on […]
Objectives To develop and validate a model to predict 12‐month continence status after robot‐assisted radical prostatectomy (RARP) from preoperative and 3‐month postoperative data; this model could help in informing patients on their individualised risk of urinary incontinence (UI) after RP in order to choose the best treatment option. Patients and Methods Data on 9421 patients […]