Videos

Vaccines for the prevention of recurrent urinary tract infections: a systematic review Abstract Objectives To systematically review the evidence regarding the efficacy of vaccines or immunostimulants in reducing the recurrence rate of urinary tract infections (UTIs). Materials and Methods The Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica dataBASE (EMBASE), PubMed, Cochrane Library, World Health Organization (WHO) International Clinical Trials…

 Evaluation of axitinib to downstage cT2a renal tumours and allow partial nephrectomy: a phase II study Abstract Objective To evaluate the ability of neoadjuvant axitinib to reduce the size of T2 renal cell carcinoma (RCC) for shifting from a radical nephrectomy (RN) to a partial nephrectomy (PN) indication, offering preservation of renal function. Patients and Methods Patients with cT2aN0NxM0 clear‐cell RCC, considered not suitable for PN, were enrolled in a prospective,…

 Prostatic capsular incision during radical prostatectomy has important oncological implications. A systematic review and meta‐analysis Abstract Introduction Capsular Incision (CapI) is an iatrogenic breach of the prostatic capsule during radical prostatectomy that can cause positive surgical margins (PSM) in organ‐confined (pT2) prostate cancer (PCa), or the retention of benign prostatic tissue. We systematically interrogated the literature…

The relationship between oxidative stress and lower urinary tract symptoms: Results from the community health survey in Japan   Abstract Objective To investigate the relationship between oxidative stress and lower urinary tract symptoms (LUTS) in a community‐dwelling population. Materials and Methods The cross‐sectional study included 1 113 people who participated in the Iwaki Health Promotion Project of 2015 in Hirosaki, Japan. LUTS were assessed using structured questionnaires,…

 In utero myelomeningocele repair and urological outcomes: the first 100 cases of a prospective analysis. Is there an improvement in bladder function? Abstract   Objectives To evaluate the first 100 cases of in utero myelomeningocele (MMC) repair and urological outcomes in a prospective analysis aiming to define possible improvement in bladder function. Patients and methods We used a protocol consisting of a detailed medical history, urinary tract ultrasonography,…

The ultrasound characteristics of regions identified as suspicious by magnetic resonance imaging (MRI) predict the likelihood of clinically significant cancer on MRI–ultrasound fusion‐targeted biopsy     Abstract Objective To determine whether the presence of an ultrasound hypoechoic region at the site of a region of interest (ROI) on magnetic resonance imaging (MRI) results in improved prostate cancer (PCa) detection and predicts clinically…

This video of the week accompanies the article on Four-year outcomes from a mpMRI active surveillance programme

Does the robot have a role in radical cystectomy Abstract Between 2014 and 2015, 3742 radical cystectomies (RCs) were performed in the UK. The majority of these were open RCs (ORCs), and only 25% were performed with robot assistance. These data contrast starkly with the picture in radical prostatectomy (RP), for which most operations are robot assisted (79.4% of the 7673 in 2016). Given that most pelvic surgeons have access to robotic…

 Immediate versus delayed exercise in men initiating androgen deprivation: effects on bone density and soft tissue composition Abstract Objectives To examine whether it is more efficacious to commence exercise medicine in men with prostate cancer at the onset of androgen‐deprivation therapy (ADT) rather than later on during treatment to preserve bone and soft‐tissue composition, as ADT results in adverse effects including: reduced…