Archive for category: BJUI Blog

2019 Reviewers

Thank you to our 2019 Reviewers

We would particularly like to thank the following individuals who are the top reviewers for the journal in 2019, all with >10 reviews:

 

Andrew Elders Alexander Cole
Nathan Lawrentschuk Kelly Stratton
Janet Baack Kukreja Stacy Loeb
Robert H. Thompson Hashim Ahmed

 

We are extremely grateful to all our reviewers for their time and hard work

Aastha Abboudi, Hamid Abdollah, Firas Abern, Michael
Abufaraj, Mohammad Adam, Andy Adolfsson, Jan Adshead, James
Ahlawat, Rajesh Ahmed, Aamir Ahmed, Kamran Aho, Tev
Al Jaafari, Feras Albersen, Maarten Albertsen, Peter Albuquerque, Emanuel
Ambrosio, Maria Amoroso, Peter Amparore, Daniele Anastasiadis, Anastasios
Anderson, Paul Andersson, Karl-Erik Andriole, Gerald Anele, Uzoma
Antonelli, Jodi Apostolidis, Apostolos Arora, Sohrab Asplin, John
AUDENET, François Auvinen, Anssi Aydin, Abdullatif Baard, Joyce
Bachmann, Lucas Ball, Mark Barber, Neil Barod, Ravi
Basak, Ram Becerra, Maria F. Beckmann, Kerri Bedke, Jens
Beiles, Charles Barry Berger, Lorenz Bertolo, Riccardo Beyer, Burkhard
Beyer, Katharina Bhandari, Mahendra Bianchi, Lorenzo Bishop, Conrad
Bivalacqua, Trinity Blaivas, Jerry Blecher, Gideon Blok, Bertil
Blute, Michael Bodie, Joshua Bogaert, Guy Bokhorst, Leonard
Bolgeri, Marco Bolton, Damien Boorjian, Stephen Borofsky, Michael S.
Borza, Tudor Bouchier-Hayes, David Bowers, Aaron BOZKURT, Ibrahim
Braga, Luis Bratt, Ola Bravi, Carlo Andrea Breau, Rodney
Brembilla, Giorgio Breyer, Benjamin Brown, Christian Brown, Matthew
Buckley, Jill Budäus, Lars Bujons, Anna Bultitude, Matthew
Burger, Maximilian Buscarini, Maurizio Cahill, Declan Calvert, Robert
Campi, Riccardo Canales, Benjamin K. Canda, Abdullah Cantiello, Francesco
Capece, Marco Capogrosso, Paolo Carillo, Mauro CARLO, BUONERBA
Castellani, Daniele Castiglione, Fabio Cathcart, Paul Cayan, Selahittin
Celia, Antonio Celik, Serdar Cellek, Selim Challacombe, Ben
Chandak, Pankaj Chandra, Ashish Chandrasekar, Thenappan Chang, Peter
Chapin, Brian Chapple, Christopher Chartier-Kastler, Emmanuel Checcucci, Enrico
Chee, Justin Chemasle, Christophe Chen, Jian Chen, Qi
Chen, Ronald Chew, Ben Chi, Thomas Chin, Joseph
Chin, Peter Chiong, Edmund Chiriaco, Giovanni Cho, Kang Su
Cho, Min Chul Choi, Haesun Choi, Seungtaek Choong, Simon
Christopher, Andrew Chudek, Jerzy Chung, Jinsoo Clark, Peter
Cocci, Andrea Collins, Justin Connell, Shea Connolly, Stephen
Cook, Gary Costello, Anthony Cranston, David Crawford, David
Cresswell, Joanne Crestani, Alessandro Cruz, Célia Cruz, Francisco
Culig, Zoran Cumberbatch, Marcus Cutress, Mark Dahm, Philipp
Dall’Era, Marc Damber, Jan-Erik Dangle, Pankaj Danilack, V. A.
Danuser, Hansjoerg Das, Akhil DasGupta, Ranan Davis, John
Davis, Niall de Castro Abreu, Andre Luis De La Rosette, Jean De Luca, Stefano
De Nunzio, Cosimo Del Popolo, Giulio Delahunt, Brett Dell’Oglio, Paolo
Denstedt, John Desai, Janak Desai, Mahesh Deshpande, Aniruddh
Di Muzio, Nadia Ding, Maylynn Dinkelman-Smit, M. Dizman, Nazli
Djordjevic, Miroslav Dmochowski, Roger Downing, Amy Dragos, Laurian
Dudderidge, Tim Dukic, Ivo Dundee, Philip Eardley, Ian
Eberli, Daniel Eden, Christopher Efstathiou, Jason Ehdaie, Behfar
Eisner, Brian El-Ghoneimi, Alaa Elhage, Oussama Elliott, Sean
Elshal, Ahmed Elsheikh, Mohamed Elterman, Dean Emberton, Mark
Emiliani, Esteban Engeler, Daniel Enting, Deborah Epstein, Jonathan
Erci, Behice Everaert, Karel Everaerts, Wouter Fajkovic, Harun
Falagario, Ugo Farhat, Walid Ferriero, MariaConsiglia Ferro, Matteo
Ficarra, Vincenzo Figg, William Filson, Christopher Finch, William
Fiorini, Paolo Fisch, Margit Fisher, Rebecca Fishman, Mayer
Fleshner, Neil Fletcher, Sean Fok, Cynthia Fong, Eva
Foo, Keong Tatt Foreman, Darren Fraundorfer, Mark Friberg, Anne Sofie
Froehner, Michael Frydenberg, Mark Gacci, Mauro Gadzhiev, Nariman
Gakis, Georgios Galfano, Antonio Ghagane, Shridhar C. Ghani, Khurshid
Ghose, Amit Giannantoni, Antonella Giannarini, Gianluca Giganti, Francesco
Gild, Philipp Gill, Inderbir Gilling, Peter Giusti, Guido
Gokce, Mehmet Ilker Goldfarb, David Goldman, Howard Gontero, Paulo
Goossen, Hans Gordon, Stephen Gore, John Gorin, Michael
Graefen, Markus Gray, Elin Greenwell, Tamsin Gregg, Justin
Grey, Alistair Grey, Benjamin Gross, Andreas Gross, Martin
Grummet, Jeremy Gu, Meng Gulati, Roman Gundeti, Mohan
Gupta, Mohit Gupta, Nikhil K. Guru, Khurshid Guruli, Georgi
Habous, Mohamad Hackett, Geoff Hadjipavlou, Marios Hahn, Andrew
Hamid, Rizwan Hamidi, Nurullah Han, Bangmin Han, Misop
Hanna, Nawar Hanno, Philip Hart, Nicolas Hasan, Mudhar
Häuser, Lorine Heesakkers, John Hegarty, Paul Heidenreich, Axel
Heller, Nick Hemal, Ashok Hennessey, Derek Herlemann, Annika
Hevia, Mateo Hindley, Richard Hsi, Ryan S. Huang, Jay
Hubscher, Charles Huddart, Robert Hughes, Francis Hughes, Simon
Hung, Andrew Hwang, Eu Chang Ilg, Marcus Ingham, Matthew
Irtan, Sabine Irving, Stuart Jack, Greg Jeldres, Claudio
Jeong, Chang Wook Jiwane, Ashish Johnson, Mark Joseph, Jean
Joshi, Pankaj Jung, Jae Hung Kadıoğlu, Ateş Kahokehr, Arman
Kalapara, Arveen Kalejaiye, Ayo Kamat, Ashish Kapoor, Jada
Karakiewicz, Pierre Karam, Jose Karunanithy, Narayan Kasivisvanathan, Veeru
Kavoussi, Louis Kaynar, Mehmet Keeley, Frank Kemal, Sarica
Khan, Azhar Khochikar, Makarand Khoubehi, Bijan Kim, Isaac
Kim, Jae Heon Kim, Simon King, Martin Kirby, Michael
Kirkman, Maggie Kirsch, Andrew Kirschner-Hermanns, Ruth Kishan, Amar
Kitta, Takeya Klaassen, Zachary Klatte, Tobias Knudsen, Bodo
Koch, Michael Kockelbergh, Roger Konety, Badrinath Koo, Kevin
Kosaka, Takeo Kowalczyk, Anna Kowalewski, Tim Krambeck, Amy
Krasnow, Ross Krauss, Daniel J. Krimphove, Marieke Kryvenko, Oleksandr
Kulkarni, Ravi Kulkarni, Sanjay Kumar, Sunil Kundu, Bibhas
Kuo, Hann-Chorng Kusaka, M. Kutlu, Omer Kwon, Ohseong
Lam, Wayne Lamb, Alastair Lamb, Benjamin Lancia, Andrea
Landman, Jaime Lane, Giulia Lange, Dirk Laniado, Marc
Larcher, Alessandro Lau, Adrian Laudone, Vincent Lavallée, Luke
Lawrenson, Ross Lee, Byron Lee, David Lee, Jason Y.
Lee, Jongsoo Lee, Won Ki Lee, Young Joon Leitner, Lorenz
Lerner, Lori Lestingi, Jean Leveridge  , Michael Levine, Larry
Li, Jianxing Li, Roger LIATSIKOS, EVANGELOS Liauw, Stanley
Lieske, John Lin, Guiting Lingeman, James Lipkin, Michael
Lipshultz, Larry Liu, Hongbin Løgager, Vibeke López, Pedro José
Lotan, Tamara Ma, Runzhuo Madersbacher, Stephan Mahal, Brandon
Majima, Tsuyoshi Makanjuola, Jonathan Malde, Sachin Mamode, Nizam
Mandel, Philipp Manecksha, Rustom Manfredi, Matteo Marchioni, Michele
Mark, Stephen Marks, Leonard Martin, Richard Martinez-Salamanca, Juan
Martini, Alberto Masson-Lecomte, Alexandra Matsuda, Tadashi Mattei, Agostino
Maurer, Tobias Mayer, Erik Mazzone, Elio Mazzucchi, Eduardo
McCammon, Kurt McClintock, Tyler McGrath, John McNeill, Alan
McNeill, S McNicholas, Thomas Mehan, Nicholas Mehnert, Ulrich
Menichetti, Julia Meyer, Christian Milenkovic, Uros Minhas, Suks
Mir, Maria Misrai, Vincent Mizokami, Atsushi Mizuno, Kentaro
Modgil, Vaibhav Modi, Parth Modonutti, Daniele Moncada, Ignacio
Monga, Manoj Montanari, Emanuele Montorsi, Francesco Moochhala, Shabbir
Moon, Daniel Moore, Caroline Moran, Diarmaid Morel Journel, Nicolas
MORETTI, KIM Morey, Allen F. Moschini, Marco Mossanen, Matthew
Mostafid, Hugh MOURMOURIS, PANAGIOTIS Mout, Lisanne Muir, Gordon
Mukhopadhyay, Subhankar Mumtaz, Faiz Mundy, Anthony Muneer, Asif
Murphy, Adam Murphy, Declan Muschter, Rolf Nabi, Junaid
Nair, Shiva Najari, Bobby Narayan, Vikram Nathan, Senthil
Nazzani, Sebastiano Netsch, Christopher Nguyen, David-Dan Nicolai, Nicola
Norberto, Bernardo Novara, Giacomo Nunes-Silva, Igor O’Brien, Timothy
Odisho, Anobel Ogden, Chris Ohlander, Samuel O’Kelly, Fardod
Olsburgh, Jonathon Onem, Kadir Osmonov, Daniar Ost, Piet
Ozyavuz, Rasin Paciotti, Marco Pais, Jr., Vernon Pais, Vernon
Pal, Sumanta Panach-Navarrete, J. Pang, See‑Tong Panicker, Jalesh
Pannek, Jürgen Pariser, Joseph Patel, Hiten Patel, Nishant
Patel, Prashant Patel, Vipul Paterson, Ryan Patterson, Jake
Paul, Asit Pavlovich, Christian Pearce, Ian Pearce, Shane
Pearle, Margaret Penson, David Peters, Kenneth Pierorazio, Phillip
Pinsky, Paul Pontari, Mike Popert, Richard Porpiglia, Francesco
Porten, Sima Porter, James Portis, Andrew Potretzke, Aaron
Preminger, Glenn Presicce, Fabrizio Preston, Mark Purohit, Rajveer
Radtke, Jan Philipp Rai, Bhavan Rais-Bahrami, Soroush Raison, Nicholas
Ralph, David Ramakrishnan, Venkat Ramani, Vijay Ramasamy, Ranjith
Ramaswamy, Ashwin Ramón de Fata, Fernando Ranasinghe, Weranja Randhawa, Karen
Rane, Abhay Rashid, Prem Rassweiler, Jens Rastinehad, Ardeshir
Ratan, Hari Reddy, Sumeet Rees, Geraint Rees, Rowland
Reese, Stephen Reiter, Robert Resorlu, Berkan Rha, Koon Ho
Rink, Michael Rivera, Marcelino Riza Kural, Ali Robert, Grégoire
Roberts, Matthew Robertson, William Robinson, David Rocco, Bernardo
Rogers, Alistair Rogers, Craig Roghmann, Florian Roobol, Monique
Rose, Brent Roseman, John Ross, Ashley Roth, Beat
Rottenberg, Giles Rukin, Nicholas Rule, Andrew Russell, Beth
Russo, Giorgio Ivan Sabnis, Ravindra Sade, Recep Sahai, Arun
Sakellariou, Christina Alexandra Salami, Simpa Salonia, Andrea Salter, Carolyn
Samaratunga, Hemamali Sammon, Jesse Samnakay, Naeem Samplaski, Mary
Sanchez-Salas, Rafael Sangster, Philippa Sarica, Kemal Sas, David
Sathianathen, Niranjan Schaeffer, Edward Schiavina, Riccardo Schmid, Marianne
Schutzer, Matthew Sedigh, Omid Segaran, Surayne Seisen, Thomas
Sellitti, Donald Semins, Michelle Sengupta, Shomik Sethia, Krishna
Sfakianos, John Shao, Yi Shaw, Greg Shigemura, Katsumi
Shiranov, Kirill Shrotri, Nitin Shukla, Aseem Silverman, Joshua
Singh, Avinash Siva, Shankar Skarecky, Douglas Skolarus, Ted
Smith, Angela Smith, Arthur Smith, Thomas Soares, Ricardo
Soderberg, Leah Sodha, Hiren Soeterik, Timo Sofer, Mario
Sofikitis, Nikolaos Sokoll, Lori Somani, Bhaskar Sonpavde, Guru
Sood, Akshay Soomro, Naeem Sooriakumaran, Prasanna Speakman, Mark
Spiess, Phillippe Spratt, Daniel Srinivasan, Arun Stai, Bethany
Stamatakis, Lambros Standring, Susan Stattin, Pär Stebbing, Justin
Stephan, Carsten Stewart, Grant Stish, Bradley Stoianovici, Dan
Stone, Nelson Stricker, Phillip Stroman, Luke Studd, Rodney
Suardi, Nazareno Subudhi, Sumit Sujenthiran, Arunan Sundi, Debasish
Sur, Roger Swann, Ray Tae, Bum Sik Tailly, Thomas
Takagi, Toshio Tan, Wei Shen Tay, Kae Jack Taylor, Claire
Te, Alexis Teichman, Joel Teoh, Jeremy Tewari, Ash
Thalmann, George Thimmegowda, Manohar Thomas, Kay Thurairaja, Ramesh
Tikkinen, Kari Tilki, Derya Torremade Barreda, Josep Tosoian, Jeffrey
Tran, Maxine Trinh, Quoc-Dien Trinh, Vincent Tsivian, Matvey
Tu, Shi-Ming Tubaro, Andrea Tully, Karl Turajlic, Samra
Turney, Ben Ukimura, Osamu Urkmez, Ahmet Uruc, Fatih
Uzzo, Robert van den Bergh, Roderick Van der Aa, Frank Van der Kwast, Theodorus
Van Hemelrijck, Mieke van Kerrebroeck, Philip van Renterghem, Koenraad van Rij, Simon
Vanni, Alex Vasdev, Nikhil Vasdev, Nikhil Vela, Ian
Verma, Hema Vernooij, Robin Vicentini, Fabio C Villers, Arnauld
Vivian, Justin Wagenlehner, Florian Wallis, Christopher Walsh, Anna
Walsh, Patrick Walton, Thomas Wang, Shaogang Wang, Ye
Ward, John Warner, Jonathan Watanabe, Hiroki Watkin, Nick
Watson, William Weight, Christopher Weizer, Alon Welk, Blayne
Westney, Ouida Weston, Robin White, Jared Williams, Michael
Williams, Stephen Willis, Susan Winkle, David Wiseman, Oliver
Withington, John Wong, Kathie Wong, Lih-Ming Woo, Henry
Woo, Sungmin Wood, Dan Woon, Dixon Teck Sing Wright, Anne
Wu, Wenqi Wyant, Cole Wysock, James Xu, Kewei
Xylinas, Evanguelos Yafi, Faysal Yang, Dong-Rong Yap, Tet
Yassaie, Omid Yaxley, John Ye, Dingwei Yoshimura, Naoki
Zamboglou, Constantinos Zamboni, Stefania Zargar, Homi Zeng, Guohua
Zhao, Lee Zhu, Gang Zhu, Xiaoye Zondervan, Patricia
Zorn, Kevin

 

 

We look forward to working with you again in 2020.

 

Residents’ podcast: Exercise-induced attenuation of treatment side effects in newly diagnosed PCa patients beginning androgen-deprivation therapy

Maria Uloko is a Urology Resident at the University of Minnesota Hospital. In this podcast she discusses a recent Article of the month:

Exercise‐induced attenuation of treatment side‐effects in patients with newly diagnosed prostate cancer beginning androgen‐deprivation therapy: a randomised controlled trial

Abstract

Objectives

(i) To assess whether exercise training attenuates the adverse effects of treatment in patients with newly diagnosed prostate cancer beginning androgen‐deprivation therapy (ADT), and (ii) to examine whether exercise‐induced improvements are sustained after the withdrawal of supervised exercise.

Patients and Methods

In all, 50 patients with prostate cancer scheduled for ADT were randomised to an exercise group (n = 24) or a control group (n = 26). The exercise group completed 3 months of supervised aerobic and resistance exercise training (twice a week for 60 min), followed by 3 months of self‐directed exercise. Outcomes were assessed at baseline, 3‐ and 6‐months. The primary outcome was difference in fat mass at 3‐months. Secondary outcomes included: fat‐free mass, cardiopulmonary exercise testing variables, QRISK®2 (ClinRisk Ltd, Leeds, UK) score, anthropometry, blood‐borne biomarkers, fatigue, and quality of life (QoL). HealthEd Academy can provide an extensive guides about bodybuilding, the best SARMs, Anadrole reviews and much more, take a look!

Results

At 3‐months, exercise training prevented adverse changes in peak O2 uptake (1.9 mL/kg/min, P = 0.038), ventilatory threshold (1.7 mL/kg/min, P = 0.013), O2 uptake efficiency slope (0.21, P = 0.005), and fatigue (between‐group difference in Functional Assessment of Chronic Illness Therapy‐Fatigue score of 4.5 points, P = 0.024) compared with controls. After the supervised exercise was withdrawn, the differences in cardiopulmonary fitness and fatigue were not sustained, but the exercise group showed significantly better QoL (Functional Assessment of Cancer Therapy‐Prostate difference of 8.5 points, P = 0.034) and a reduced QRISK2 score (−2.9%, P = 0.041) compared to controls.

Conclusion

A short‐term programme of supervised exercise in patients with prostate cancer beginning ADT results in sustained improvements in QoL and cardiovascular events risk profile.

BJUI Podcasts are available on iTunes: https://itunes.apple.com/gb/podcast/bju-international/id1309570262

Residents’ podcast: Health‐related quality of life among non‐muscle‐invasive bladder cancer survivors: a population‐based study

Maria Uloko is a Urology Resident at the University of Minnesota Hospital. In this podcast she discusses a recent Article of the week:

Health‐related quality of life among non‐muscle‐invasive bladder cancer survivors: a population‐based study

Abstract

Objective

To examine the effect of non‐muscle‐invasive bladder cancer (NMIBC) diagnosis and treatment on survivors’ quality of life (QoL).

Patients and Methods

Of the 5979 patients with NMIBC diagnosed between 2010 and 2014 in North Carolina, 2000 patients were randomly selected to be invited to enroll in this cross‐sectional study. Data were collected by postal mail survey. The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire‐Core (QLQ‐C30) and the NMIBC‐specific module were included in the survey to measure QoL. Descriptive statistics, t‐tests, anova, and Pearson’s correlation were used to describe demographics and to assess how QoL varied by sex, cancer stage, time since diagnosis, and treatment.

Results

A total of 398 survivors returned questionnaires (response rate: 23.6%). The mean QoL score for QLQ‐C30 (range 0–100, higher = better QoL in all domains but symptoms) for global health status was 73.6, function domain scores ranged from 83.9 to 86.5, and scores for the top five symptoms (insomnia, fatigue, dyspnoea, pain, and financial difficulties) ranged from 14.1 to 24.3. The lowest NMIBC‐specific QoL domain was sexual issues including sexual function, enjoyment, problems, and intimacy. Women had worse bowel problems, sexual function, and sexual enjoyment than men but better sexual intimacy and fewer concerns about contaminating their partner. Stage Ta had the highest global health status, followed by T1 and Tis. QoL did not vary by time since diagnosis except for sexual function. The cystectomy group (n = 21) had worse QoL in sexual function, discomfort with sexual intimacy, sexual enjoyment, and male sexual problems than the non‐cystectomy group (n = 336).

Conclusion

Survivors of NMIBC face a unique burden associated with their diagnosis and the often‐lifelong surveillance and treatment regimens. The finding has important implications for the design of tailored supportive care interventions to improve QoL for NMIBC survivors.

BJUI Podcasts are available on iTunes: https://itunes.apple.com/gb/podcast/bju-international/id1309570262

January 2020 – About the cover

The first Article of the Month for 2020 is from work carried out at Northumbria University in Newcastle, Norfolk and Norwich University Hospital, both in the UK, and James Cook University in Queensland, Australia (Exercise-induced reduction of ADT side-effects in newly diagnosed PCa patients beginning androgen‐deprivation therapy: a randomised controlled trial). The article discusses the benefits of exercise in improving quality of life and reducing cardiovascular events following treatment for prostate cancer.

The cover image shows the city of Newcastle during the Great North Run – the city’s iconic half marathon – which takes place every year in September.  It was created by former Olympic Bronze 10, 000m medalist, Brendan Foster, in 1981 and in 2014 the one millionth runner crossed the finish line.

©shutterstock

90 years of BJU International

This blog marks the launch of the British Journal of Urology 90 years ago.  Since then the Journal has undergone many changes as urology and the publishing environment have changed. The first Editors outlined their vision in the Foreword of the first issue, which includes an introduction to the speciality, the locations and opening hours of Urology Clinics and a plea for peace:

The British Journal of Urology Vol.1 1929

From the outset, the Editors placed emphasis on seeking collaboration and contributions internationally. From 1929 up to 1942 there was even a section in the Journal advising urologists visiting London where to find details of urological clinics which they could visit.

This time-table is published in each number of the Journal for the guidance of travelling medical practitioners who may wish to visit Urological Clinics.

Visitors to London are advised to call at No.1 Wimpole St, W.1, where daily bulletins of operations and lectures issued by the Fellowship of Medicine are available for inspection….”

 

 

 

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A sample of the advertisements included in the first edition shows the kit available at the time.

 

 

 

 

Articles

The first two pages of the very first article are reproduced here and can be accessed via Wiley Online. Note the detailed hand-drawn diagrams. It is also interesting to note the lack of articles on prostate cancer – very different from a urological journal of today.

Collaboration

In 1946 the Journal included a report on “… the Inaugural Scientific Meeting of the British Association of Urological Surgeons and acknowledged the importance of taking on “…the role of official organ of the B.A.U.S….”

The Journal is proud to continue to be an official journal of BAUS and to be the official journal of, or to be affiliated with, many urological associations around the world including:

Urological Society of Australia and New Zealand

Urological Society of India

Caribbean Urological Association

Hong Kong Urological Association

Irish Society of Urology

Swiss Continence Foundation

Korean journal, Investigative and Clinical Urology

Indonesian Urological Association

International Alliance of Urolithiasis

Malaysian Urological Association.

The Journal was, of course, solely a paper-based one from inception until 1994 when content was made available on CD ROM.  This innovation was soon superseded by the advent of the internet and the Journal was first published online in 1997. This signal event resulted in a transformation of the procedure for submitting and processing papers through peer review from a paper-based, postal one to an online one. All articles published in the Journal since 1929 have been digitised so that they are accessible online. Over the last two decades, the demand for print subscriptions has waned.

In 1999 the name of the Journal was changed to BJU International, reflecting the Journal’s British heritage and the importance of the contributions from the UK and internationally.

BJUI Editors 1929-2019

Responsibility for the Journal has been held by a succession of Editors and their Editorial Teams. There have been 10 editors during the first 90 years, some of whom served as co-editors (early version of a job-share?).

1929-1933

Frank Kidd & HP Winsbury White

1933-1948

HP Winsbury White

1949-1966

David Band

1967-1972

JD Fergusson

1972-1977

W Keith Yeates

1978-1993

GD Chisholm

1994-1996

Hugh Whitfield & Bill Hendy

1997-2002

Hugh Whitfield

2003-2012

John Fitzpatrick

2013-2020

Prokar Dasgupta

Thanks to Jonathan Goddard for the photos of the editors

Our current Editor-in-Chief, Prokar Dasgupta, is supported by an internationally based team of Associate Editors and Consulting Editors. In August next year, he will hand on the Editorship to Freddie Hamdy.

Thank you to our Editorial Teams, authors and peer reviewers for all their hard work in contributing to the success of the Journal.

 

 

IP4-CHRONOS is launched

IP4- CHRONOS is open! CHRONOS is a phase II randomised control trial, that will review the outcomes (including oncological, functional, quality of life and cost-effectiveness) of focal therapy against those from radical therapy, in men with newly diagnosed localised clinically significant prostate cancer.

 

 

All men newly diagnosed with low-intermediate risk prostate cancer, confined to the prostate, with a life expectancy of at least 10 years will be screened for eligibility. Men must be well enough to undergo the interventions outlined in the trial prior to being enrolled.

Men will then have a choice of enrolling into CHRONOS A or CHRONOS B. CHRONOS A will randomise men to having radical whole gland treatment (radiotherapy, brachytherapy or prostatectomy), or focal therapy (HIFU or cryotherapy). CHRONOS A will answer the question, ‘is focal therapy equivalent in cancer control as radical therapy?’ CHRONOS B will randomise men to having focal therapy with or without additional neoadjuvant treatment and will answer the question: ‘can the success of focal therapy be improved by using neoadjuvant treatment?’ Randomisation will be stratified by disease characteristics.

All men will undergo intervention as they would within the NHS, however by doing so in a trial setting, we can directly compare the results of such treatments against each other. As the follow up mimics that of standard of care, the extra burden of treatment within the trial is minimal.

60 men will be recruited into both CHRONOS A and CHRONOS B (total 120) over a 1-year period, during the pilot, and if recruitment is successful the aim is to continue to a larger study assessing 2450 patients over 5 years, with a minimum follow up of 3 years. The primary outcome measures will be progression free survival in CHRONOS A, and failure free survival in CHRONOS B. The CHRONOS pilot will open in 12 UK hospital sites, aiming to open across the UK and Europe within the larger study.

CHRONOS is entirely funded by the Prostate Cancer UK charity, and available on the NIHR CRN portfolio. If you would like to join the main phase of CHRONOS as a site, please contact Miss Deepika Reddy ([email protected]) or visit our website for further information www.imperialprostate.org.uk/CHRONOS

Prof Hashim U. Ahmed (CHRONOS PI&CI)

Mr Taimur T. Shah (CHRONOS sub-investigator, Urology SpR & Research Fellow)

Miss Deepika Reddy (CHRONOS Clinical Research Fellow)

 

December 2019 – About the cover

The lead authors of this month’s selected article (Three‐dimensional virtual imaging of renal tumours: a new tool to improve the accuracy of nephrometry scores) are from the University of Turin, Italy (UNITO). This university was founded in 1404 making it one of the oldest universities in the World. It has been through some turbulent times but more recently can claim three nobel prize winners: Salvador LuriaRenato Dulbecco and Rita Levi-Montalcini.

The cover image shows the city of Turin at sunset. Turin sits mainly on the Po River and it is surrounded by the Western Alps. As the 10th most visited city in Italy it is known for The shroud of Turin, and its football teams (Juventus and Torino). It is also a cultural centre with many theatres, restaurants, art galleries, palaces, parks and churches.

 

 

©istock.com/fabio lamanna

 

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